英文名稱
(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
純度
>95% (HPLC)
網頁展示純度為入庫指導純度值,各批次間存在一定差異,實際純度以收貨為準
White to Pale Beige Solid
Chloroform (Slightly), Dichloromethane (Sparingly), DMSO (Slightly), Methanol (S
Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is the counterpart to (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, the latter enantiomer being a key intermediate in the preparation of Solifenacin (S676700), an antimuscarinic agent. Since (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is produced as a by-product, it has been suggested that it should be recycled in order to obtain the S enantiomer on a larger scale. (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is also used as a reagent to prepare quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives, compounds that act as muscarinic receptor antagonists.