英文名稱
(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
(E)-2-氰基-3-(3-乙氧基-4-羥基-5-硝基苯基)-N,N-二乙基丙烯酰胺 (恩他卡朋雜質)
Smiles Code
CCOc1cc(\C=C(/C#N)\C(=O)N(CC)CC)cc(c1O)[N+](=O)[O-]
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
(2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.