英文名稱
(R)-Afatinib
(R,E)-N-(4-((3-氯-4-氟苯基)氨基)-7-((四氫呋喃-3-基)氧基)喹唑啉-6-基)-4-(二甲基氨基)但是- 2-烯酰胺(阿法替尼雜質)
Smiles Code
O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@H]4COCC4)/C=C/CN(C)C
純度
>95% (HPLC)
網頁展示純度為入庫指導純度值,各批次間存在一定差異,實際純度以收貨為準
Pale Beige to Pale Brown Solid
DMSO (Slightly), Methanol (Slightly)
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3R)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide, is an impurity of Afatinib (A355300) an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.