Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
4’-Deschloro Cetirizine is an impurity of cetirizine. Cetirizine is a nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Antihystaminic.
參考文獻
Gosar, A., et al.: World J. Pharm. Res., 7, 1209 (2018); De Vos, C., et al.: Ann. Allergy, 59, 278 (1987), Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987), Fadel, R., et al.: Clin. Allergy, 17, 373 (1987), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)