Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
1,3-Bis[(1-methylethyl)amino]-2-propanol (Metoprolol EP Impurity M) is an impurity of Metoprolol (M338790), a β1 selective aryloxypropanolamine andrenergic antagonist which ois used in the treatment of a variety of cardiovascular disorder (1,2). Antihypertensive; antianginal; antiarrhythmic (class II).
參考文獻
1. Johansson, B. et al.: Eur J Pharmacol. 1973 Nov;24(2):194-204.2. Benfield, P. et al.: Drugs. 1986 May;31(5):376-429.