英文名稱
(betaS,deltaS)-Atorvastatin tert-Butyl Ester
(3S,5S)-7-(2-(4-氟苯基)-5-異丙基-3-苯基-4-(苯基氨基甲酰基)-1H-吡咯-1-基)-3,5-二羥基庚酸叔丁酯
Smiles Code
CC(C)c1c(C(=O)Nc2ccccc2)c(c3ccccc3)c(c4ccc(F)cc4)n1CC[C@H](O)C[C@H](O)CC(=O)OC(C)(C)C
Research Tools; Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
(βS,δS)-Atorvastatin tert-Butyl Ester is an intermediate used in the synthesis of (3S,5S)-Atorvastatin Sodium Salt (A791735), which is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.