Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
應用
5-Acetylsalicylamide is used as a reagent in the synthesis of Phosphotyrosine(P365000) peptidomimetic prodrugs, compounds that have similar structure to small protein-like chains in order to mimic peptide activities. 5-Acetylsalicylamide is also used as a reagent to prepare 4-aminopiperidine ureas, compounds that act as human b3 adrenergic receptor agonists.
參考文獻
Ashwell, M., et al.: Bioorgan. Med. Chem. Lett., 11, 3123 (2001); Garrido-Hernandez, H., et al.: J. Med. Chem., 49, 3368 (2006)