產品編號
1237639
CAS 號
32004-67-4
中文名稱
(E/Z)-Sulindac sulfide
MDL 號
MFCD00869764
分子量
340.41
存儲條件
2-8°C
網頁展示純度為入庫指導純度值,各批次間存在一定差異,實際純度以收貨為準
熔點
189-191 °C
沸點
526.3±50.0 °C at 760 mmHg
閃點
旋光
描述
TPSA
37.3
LogP
5.35
H_Acceptors
2
H_Donors
1
Rotatable_Bonds
4
[1]. Richter L, et al. Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602.
[2]. Dessislava Mladenova, et al. Sulindac activates NF-κB signaling in colon cancer cells. Cell Commun Signal. 2013 Oct 1:11:73.
[3]. Haruhiko Watahiki, et al. CTF1-51, a truncated carboxyl-terminal fragment of amyloid precursor protein, suppresses the effects of Aβ42-lowering γ-secretase modulators. Neurosci Lett. 2012 Sep 27;526(2):96-9.
[4]. Jason L Liggett, et al. Anti-tumor activity of non-steroidal anti-inflammatory drugs: cyclooxygenase-independent targets. Cancer Lett. 2014 May 1;346(2):217-24.
[5]. Johanna Wanngren, et al. Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production. J Biol Chem. 2012 Sep 21;287(39):32640-50.
警示圖
警示詞
Warning
危險申明
H302-H317-H334-H361
警告申明
P261-P264-P270-P272-P280-P284-P302+P352-P304+P340-P330-P362+P364-P405-P501
GHS 編碼
GHS07,GHS08
現貨供應
專業護航
售后無憂
品質保障
無需湊單