Standards; Pharmaceutical/API Drug Impurities/Metabolites;
應用
(R)-Betaxolol is the R-isomer of Betaxolol (B328000), a cardioselective b1-adrenergic blocker (1,2,3). It is also an antihypertensive and antiglaucoma agent (4).
參考文獻
(1) Bickel, M., et al.: J. Pharm. Pharmacol., 32, 669 (1980)(2) Cadigan, P.J., et al.: Br. J. Clin. Pharmacol., 9, 569 (1980) (3) Pathe, M., et al.: Therapie, 37, 75 (1982)(4) Panchal, V. S., et al.: J. Pharm. Sci. Pharmacol. 2, 21 (2015)